Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure

Cigarette smoking (CS), the main risk factor for COPD (chronic obstructive pulmonary disease) in developed countries, decreases alveolar macrophages (AM) clearance of both apoptotic cells and bacterial pathogens. This global deficit of AM engulfment may explain why active smokers have worse outcomes...

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Publicado en:PLoS One
Autores principales: Serban, Karina A., Petrusca, Daniela N., Mikosz, Andrew, Poirier, Christophe, Lockett, Angelia D., Saint, Lauren, Justice, Matthew J., Twigg, Homer L., Campos, Michael A., Petrache, Irina
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407578/
https://ncbi.nlm.nih.gov/pubmed/28448535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176073
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