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Active Trafficking of Alpha 1 Antitrypsin across the Lung Endothelium
The homeostatic lung protective effects of alpha-1 antitrypsin (A1AT) may require the transport of circulating proteinase inhibitor across an intact lung endothelial barrier. We hypothesized that uninjured pulmonary endothelial cells transport A1AT to lung epithelial cells. Purified human A1AT was r...
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| Autori principali: | , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3990572/ https://ncbi.nlm.nih.gov/pubmed/24743137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093979 |
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