Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure

Cigarette smoking (CS), the main risk factor for COPD (chronic obstructive pulmonary disease) in developed countries, decreases alveolar macrophages (AM) clearance of both apoptotic cells and bacterial pathogens. This global deficit of AM engulfment may explain why active smokers have worse outcomes...

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Vydáno v:PLoS One
Hlavní autoři: Serban, Karina A., Petrusca, Daniela N., Mikosz, Andrew, Poirier, Christophe, Lockett, Angelia D., Saint, Lauren, Justice, Matthew J., Twigg, Homer L., Campos, Michael A., Petrache, Irina
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407578/
https://ncbi.nlm.nih.gov/pubmed/28448535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176073
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