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Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency

Alpha-1-antitrypsin deficiency (AATD), also known as alpha1-proteinase inhibitor deficiency, is an autosomal co-dominant condition. The genotypes associated with AATD include null, deficient, and dysfunctional alpha-1-antitrypsin (A1AT) variants, which result in low levels of circulating functional...

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Bibliographic Details
Main Authors: Petrache, Irina, Hajjar, Joud, Campos, Michael
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726081/
https://ncbi.nlm.nih.gov/pubmed/19707408
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