Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure

Cigarette smoking (CS), the main risk factor for COPD (chronic obstructive pulmonary disease) in developed countries, decreases alveolar macrophages (AM) clearance of both apoptotic cells and bacterial pathogens. This global deficit of AM engulfment may explain why active smokers have worse outcomes...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Serban, Karina A., Petrusca, Daniela N., Mikosz, Andrew, Poirier, Christophe, Lockett, Angelia D., Saint, Lauren, Justice, Matthew J., Twigg, Homer L., Campos, Michael A., Petrache, Irina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407578/
https://ncbi.nlm.nih.gov/pubmed/28448535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176073
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