ANGPTL3 Deficiency and Protection Against Coronary Artery Disease

BACKGROUND: Familial combined hypolipidemia, a Mendelian condition characterized by substantial reductions in all 3 major lipid fractions, is caused by mutations that inactivate the gene angiopoietin-like 3 (ANGPTL3). Whether ANGPTL3 deficiency reduces risk of coronary artery disease (CAD) is unknow...

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書誌詳細
出版年:J Am Coll Cardiol
主要な著者: Stitziel, Nathan O., Khera, Amit V., Wang, Xiao, Bierhals, Andrew J., Vourakis, A. Christina, Sperry, Alexandra E., Natarajan, Pradeep, Klarin, Derek, Emdin, Connor A., Zekavat, Seyedeh M., Nomura, Akihiro, Erdmann, Jeanette, Schunkert, Heribert, Samani, Nilesh J., Kraus, William E., Shah, Svati H., Yu, Bing, Boerwinkle, Eric, Rader, Daniel J., Gupta, Namrata, Frossard, Philippe M., Rasheed, Asif, Danesh, John, Lander, Eric S., Gabriel, Stacey, Saleheen, Danish, Musunuru, Kiran, Kathiresan, Sekar
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404817/
https://ncbi.nlm.nih.gov/pubmed/28385496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2017.02.030
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