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Genetic association of waist-to-hip ratio with cardiometabolic traits, type 2 diabetes and coronary heart disease

CONTEXT: In observational studies, abdominal adiposity has been associated with type 2 diabetes and coronary heart disease (CHD). Whether these associations represent causal relationships remains uncertain. OBJECTIVE: To test the association of a polygenic risk score for waist-to-hip ratio adjusted...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Emdin, Connor A., Khera, Amit V., Natarajan, Pradeep, Klarin, Derek, Zekavat, Seyedeh M., Hsiao, Allan J, Kathiresan, Sekar
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571980/
https://ncbi.nlm.nih.gov/pubmed/28196256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2016.21042
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