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Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor

BACKGROUND: UK Biobank is the world’s largest repository for phenotypic and genotypic information for individuals of European ancestry. Here, we leverage UK Biobank to understand the inherited basis for venous thromboembolism (VTE), a leading cause of cardiovascular mortality. METHODS AND RESULTS: W...

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Podrobná bibliografie
Vydáno v:Circ Cardiovasc Genet
Hlavní autoři: Klarin, Derek, Emdin, Connor A., Natarajan, Pradeep, Conrad, Mark F., Kathiresan, Sekar
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395047/
https://ncbi.nlm.nih.gov/pubmed/28373160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.116.001643
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