Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling

BACKGROUND: Nitric oxide signaling plays a key role in regulation of vascular tone and platelet activation. Here, we seek to understand the impact of a genetic predisposition to enhanced nitric oxide signaling on risk for cardiovascular diseases, thus informing the potential utility of pharmacologic...

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Udgivet i:Circulation
Main Authors: Emdin, Connor A., Khera, Amit V., Klarin, Derek, Natarajan, Pradeep, Zekavat, Seyedeh M., Nomura, Akihiro, Haas, Mary, Aragam, Krishna, Ardissino, Diego, Wilson, James G., Schunkert, Heribert, McPherson, Ruth, Watkins, Hugh, Elosua, Roberto, Bown, Matthew J, Samani, Nilesh J, Baber, Usman, Erdmann, Jeanette, Gormley, Padhraig, Palotie, Aarno, Stitziel, Nathan O., Gupta, Namrata, Danesh, John, Saleheen, Danish, Gabriel, Stacey, Kathiresan, Sekar
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771958/
https://ncbi.nlm.nih.gov/pubmed/28982690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.028021
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