Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling

BACKGROUND: Nitric oxide signaling plays a key role in regulation of vascular tone and platelet activation. Here, we seek to understand the impact of a genetic predisposition to enhanced nitric oxide signaling on risk for cardiovascular diseases, thus informing the potential utility of pharmacologic...

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Bibliografske podrobnosti
izdano v:Circulation
Main Authors: Emdin, Connor A., Khera, Amit V., Klarin, Derek, Natarajan, Pradeep, Zekavat, Seyedeh M., Nomura, Akihiro, Haas, Mary, Aragam, Krishna, Ardissino, Diego, Wilson, James G., Schunkert, Heribert, McPherson, Ruth, Watkins, Hugh, Elosua, Roberto, Bown, Matthew J, Samani, Nilesh J, Baber, Usman, Erdmann, Jeanette, Gormley, Padhraig, Palotie, Aarno, Stitziel, Nathan O., Gupta, Namrata, Danesh, John, Saleheen, Danish, Gabriel, Stacey, Kathiresan, Sekar
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771958/
https://ncbi.nlm.nih.gov/pubmed/28982690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.028021
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