DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes

A genetic predisposition to higher waist-to-hip ratio adjusted for BMI (WHRadjBMI), a measure of body fat distribution, associates with increased risk for type 2 diabetes. We conducted an exome-wide association study of coding variation in UK Biobank (405,569 individuals) to identify variants that l...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Emdin, Connor A., Khera, Amit V., Aragam, Krishna, Haas, Mary, Chaffin, Mark, Klarin, Derek, Natarajan, Pradeep, Bick, Alexander, Zekavat, Seyedeh M., Nomura, Akihiro, Ardissino, Diego, Wilson, James G., Schunkert, Heribert, McPherson, Ruth, Watkins, Hugh, Elosua, Roberto, Bown, Matthew J., Samani, Nilesh J., Baber, Usman, Erdmann, Jeanette, Gupta, Namrata, Danesh, John, Saleheen, Danish, Gabriel, Stacey, Kathiresan, Sekar
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2019
Assuntos:
Genetics/Genomes/Proteomics/Metabolomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302541/
https://ncbi.nlm.nih.gov/pubmed/30389748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0857
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados