Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development

Expanding evidence indicates multiple interactions between the hemostatic system and innate immunity, and the coagulation and complement cascades. Here we show in a tissue factor (TF)–dependent model of flow restriction-induced venous thrombosis that complement factors make distinct contributions to...

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Udgivet i:Blood
Main Authors: Subramaniam, Saravanan, Jurk, Kerstin, Hobohm, Lukas, Jäckel, Sven, Saffarzadeh, Mona, Schwierczek, Kathrin, Wenzel, Philip, Langer, Florian, Reinhardt, Christoph, Ruf, Wolfram
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Thrombosis and Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399485/
https://ncbi.nlm.nih.gov/pubmed/28223279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-749879
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