Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development

Expanding evidence indicates multiple interactions between the hemostatic system and innate immunity, and the coagulation and complement cascades. Here we show in a tissue factor (TF)–dependent model of flow restriction-induced venous thrombosis that complement factors make distinct contributions to...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Subramaniam, Saravanan, Jurk, Kerstin, Hobohm, Lukas, Jäckel, Sven, Saffarzadeh, Mona, Schwierczek, Kathrin, Wenzel, Philip, Langer, Florian, Reinhardt, Christoph, Ruf, Wolfram
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2017
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399485/
https://ncbi.nlm.nih.gov/pubmed/28223279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-749879
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