Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development

Expanding evidence indicates multiple interactions between the hemostatic system and innate immunity, and the coagulation and complement cascades. Here we show in a tissue factor (TF)–dependent model of flow restriction-induced venous thrombosis that complement factors make distinct contributions to...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Subramaniam, Saravanan, Jurk, Kerstin, Hobohm, Lukas, Jäckel, Sven, Saffarzadeh, Mona, Schwierczek, Kathrin, Wenzel, Philip, Langer, Florian, Reinhardt, Christoph, Ruf, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399485/
https://ncbi.nlm.nih.gov/pubmed/28223279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-749879
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