Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development

Expanding evidence indicates multiple interactions between the hemostatic system and innate immunity, and the coagulation and complement cascades. Here we show in a tissue factor (TF)–dependent model of flow restriction-induced venous thrombosis that complement factors make distinct contributions to...

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Subramaniam, Saravanan, Jurk, Kerstin, Hobohm, Lukas, Jäckel, Sven, Saffarzadeh, Mona, Schwierczek, Kathrin, Wenzel, Philip, Langer, Florian, Reinhardt, Christoph, Ruf, Wolfram
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2017
Schlagworte:
Thrombosis and Hemostasis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399485/
https://ncbi.nlm.nih.gov/pubmed/28223279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-749879
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