SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair

SQSTM1/p62 (sequestosome 1) selectively targets polyubiquitinated proteins for degradation via macroautophagy and the proteasome. Additionally, SQSTM1 shuttles between the cytoplasmic and nuclear compartments, although its role in the nucleus is relatively unknown. Here, we report that SQSTM1 dynami...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Autophagy
मुख्य लेखकों: Hewitt, Graeme, Carroll, Bernadette, Sarallah, Rezazadeh, Correia-Melo, Clara, Ogrodnik, Mikołaj, Nelson, Glyn, Otten, Elsje G., Manni, Diego, Antrobus, Robin, Morgan, Brian A., von Zglinicki, Thomas, Jurk, Diana, Seluanov, Andrei, Gorbunova, Vera, Johansen, Terje, Passos, João F., Korolchuk, Viktor I.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Taylor & Francis 2016
विषय:
Basic Research Papers
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391493/
https://ncbi.nlm.nih.gov/pubmed/27391408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1210368
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