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Oxidation of p62 as an evolutionary adaptation to promote autophagy in stress conditions

Ageing and age-related diseases are characterised by increased oxidative and proteotoxic stress, which results in negative effects on cell function and survival. The cell possesses several mechanisms to deal with damaged proteins, including degradation via macroautophagy (hereafter called autophagy)...

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Detalhes bibliográficos
Publicado no:Cell Stress
Main Authors: Otten, Elsje G., Stefanatos, Rhoda, Carroll, Bernadette, Korolchuk, Viktor I.
Formato: Artigo
Idioma:Inglês
Publicado em: Shared Science Publishers OG 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551744/
https://ncbi.nlm.nih.gov/pubmed/31225472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2018.04.132
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