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Oxidation of p62 as an evolutionary adaptation to promote autophagy in stress conditions

Ageing and age-related diseases are characterised by increased oxidative and proteotoxic stress, which results in negative effects on cell function and survival. The cell possesses several mechanisms to deal with damaged proteins, including degradation via macroautophagy (hereafter called autophagy)...

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Detalles Bibliográficos
Publicado en:Cell Stress
Autores principales: Otten, Elsje G., Stefanatos, Rhoda, Carroll, Bernadette, Korolchuk, Viktor I.
Formato: Artigo
Lenguaje:Inglês
Publicado: Shared Science Publishers OG 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551744/
https://ncbi.nlm.nih.gov/pubmed/31225472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2018.04.132
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