Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues

Genetic variants that modulate gene expression levels play an important role in the etiology of human diseases and complex traits. Although large-scale eQTL mapping studies routinely identify many local eQTLs, the molecular mechanisms by which genetic variants regulate expression remain unclear, par...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Liu, Xuanyao, Finucane, Hilary K., Gusev, Alexander, Bhatia, Gaurav, Gazal, Steven, O’Connor, Luke, Bulik-Sullivan, Brendan, Wright, Fred A., Sullivan, Patrick F., Neale, Benjamin M., Price, Alkes L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384099/
https://ncbi.nlm.nih.gov/pubmed/28343628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2017.03.002
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