Can Evidence from Genome-Wide Association Studies and Positive Natural Selection Surveys Be Used to Evaluate the Thrifty Gene Hypothesis in East Asians?

Yazar: Koh, Xuan-Han, Liu, Xuanyao, Teo, Yik-Ying
Baskı/Yayın Bilgisi 2014

Trans Effects on Gene Expression Can Drive Omnigenic Inheritance

Yazar: Liu, Xuanyao, Li, Yang I., Pritchard, Jonathan K.
Yayımlandı Cell (2019)

Efficiency of trans-ethnic genome-wide meta-analysis and fine-mapping

Yazar: Twee-Hee Ong, Rick, Wang, Xu, Liu, Xuanyao, Teo, Yik-Ying
Baskı/Yayın Bilgisi 2012

Evaluating the possibility of detecting evidence of positive selection across Asia with sparse genotype data from the HUGO Pan-Asian SNP Consortium

Yazar: Liu, Xuanyao, Saw, Woei-Yuh, Ali, Mohammad, Ong, Rick Twee-Hee, Teo, Yik-Ying
Baskı/Yayın Bilgisi 2014

Detecting signatures of positive selection associated with musical aptitude in the human genome

Yazar: Liu, Xuanyao, Kanduri, Chakravarthi, Oikkonen, Jaana, Karma, Kai, Raijas, Pirre, Ukkola-Vuoti, Liisa, Teo, Yik-Ying, Järvelä, Irma
Yayımlandı Sci Rep (2016)

GBAT: a gene-based association test for robust detection of trans-gene regulation

Yazar: Liu, Xuanyao, Mefford, Joel A., Dahl, Andrew, He, Yuan, Subramaniam, Meena, Battle, Alexis, Price, Alkes L., Zaitlen, Noah
Yayımlandı Genome Biol (2020)

Characterizing the genetic differences between two distinct migrant groups from Indo-European and Dravidian speaking populations in India

Yazar: Ali, Mohammad, Liu, Xuanyao, Pillai, Esakimuthu Nisha, Chen, Peng, Khor, Chiea-Chuen, Ong, Rick Twee-Hee, Teo, Yik-Ying
Baskı/Yayın Bilgisi 2014

Detecting and Characterizing Genomic Signatures of Positive Selection in Global Populations

Yazar: Liu, Xuanyao, Ong, Rick Twee-Hee, Pillai, Esakimuthu Nisha, Elzein, Abier M., Small, Kerrin S., Clark, Taane G., Kwiatkowski, Dominic P., Teo, Yik-Ying
Baskı/Yayın Bilgisi 2013

Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability

Yazar: van de Geijn, Bryce, Finucane, Hilary, Gazal, Steven, Hormozdiari, Farhad, Amariuta, Tiffany, Liu, Xuanyao, Gusev, Alexander, Loh, Po-Ru, Reshef, Yakir, Kichaev, Gleb, Raychauduri, Soumya, Price, Alkes L
Yayımlandı Hum Mol Genet (2020)

Mapping the genetic diversity of HLA haplotypes in the Japanese populations

Yazar: Saw, Woei-Yuh, Liu, Xuanyao, Khor, Chiea-Chuen, Takeuchi, Fumihiko, Katsuya, Tomohiro, Kimura, Ryosuke, Nabika, Toru, Ohkubo, Takayoshi, Tabara, Yasuharu, Yamamoto, Ken, Yokota, Mitsuhiro, Teo, Yik-Ying, Kato, Norihiro
Yayımlandı Sci Rep (2015)

Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues

Yazar: Liu, Xuanyao, Finucane, Hilary K., Gusev, Alexander, Bhatia, Gaurav, Gazal, Steven, O’Connor, Luke, Bulik-Sullivan, Brendan, Wright, Fred A., Sullivan, Patrick F., Neale, Benjamin M., Price, Alkes L.
Yayımlandı Am J Hum Genet (2017)

Linkage disequilibrium dependent architecture of human complex traits shows action of negative selection

Yazar: Gazal, Steven, Finucane, Hilary K., Furlotte, Nicholas A, Loh, Po-Ru, Palamara, Pier Francesco, Liu, Xuanyao, Schoech, Armin, Bulik-Sullivan, Brendan, Neale, Benjamin M, Gusev, Alexander, Price, Alkes L.
Yayımlandı Nat Genet (2017)

Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits

Yazar: Hormozdiari, Farhad, Gazal, Steven, van de Geijn, Bryce, Finucane, Hilary, Ju, Chelsea J.-T., Loh, Po-Ru, Schoech, Armin, Reshef, Yakir, Liu, Xuanyao, O’Connor, Luke, Gusev, Alexander, Eskin, Eleazar, Price, Alkes L.
Yayımlandı Nat Genet (2018)

The fine-scale genetic structure and evolution of the Japanese population

Yazar: Takeuchi, Fumihiko, Katsuya, Tomohiro, Kimura, Ryosuke, Nabika, Toru, Isomura, Minoru, Ohkubo, Takayoshi, Tabara, Yasuharu, Yamamoto, Ken, Yokota, Mitsuhiro, Liu, Xuanyao, Saw, Woei-Yuh, Mamatyusupu, Dolikun, Yang, Wenjun, Xu, Shuhua, Teo, Yik-Ying, Kato, Norihiro
Yayımlandı PLoS One (2017)

A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations

Yazar: Wang, Xu, Liu, Xuanyao, Sim, Xueling, Xu, Haiyan, Khor, Chiea-Chuen, Ong, Rick Twee-Hee, Tay, Wan-Ting, Suo, Chen, Poh, Wan-Ting, Ng, Daniel Peng-Keat, Liu, Jianjun, Aung, Tin, Chia, Kee-Seng, Wong, Tien-Yin, Tai, E-Shyong, Teo, Yik-Ying
Baskı/Yayın Bilgisi 2012

Insights into the Genetic Structure and Diversity of 38 South Asian Indians from Deep Whole-Genome Sequencing

Yazar: Wong, Lai-Ping, Lai, Jason Kuan-Han, Saw, Woei-Yuh, Ong, Rick Twee-Hee, Cheng, Anthony Youzhi, Pillai, Nisha Esakimuthu, Liu, Xuanyao, Xu, Wenting, Chen, Peng, Foo, Jia-Nee, Tan, Linda Wei-Lin, Koo, Seok-Hwee, Soong, Richie, Wenk, Markus Rene, Lim, Wei-Yen, Khor, Chiea-Chuen, Little, Peter, Chia, Kee-Seng, Teo, Yik-Ying
Baskı/Yayın Bilgisi 2014

Deep Whole-Genome Sequencing of 100 Southeast Asian Malays

Yazar: Wong, Lai-Ping, Ong, Rick Twee-Hee, Poh, Wan-Ting, Liu, Xuanyao, Chen, Peng, Li, Ruoying, Lam, Kevin Koi-Yau, Pillai, Nisha Esakimuthu, Sim, Kar-Seng, Xu, Haiyan, Sim, Ngak-Leng, Teo, Shu-Mei, Foo, Jia-Nee, Tan, Linda Wei-Lin, Lim, Yenly, Koo, Seok-Hwee, Gan, Linda Seo-Hwee, Cheng, Ching-Yu, Wee, Sharon, Yap, Eric Peng-Huat, Ng, Pauline Crystal, Lim, Wei-Yen, Soong, Richie, Wenk, Markus Rene, Aung, Tin, Wong, Tien-Yin, Khor, Chiea-Chuen, Little, Peter, Chia, Kee-Seng, Teo, Yik-Ying
Baskı/Yayın Bilgisi 2013

Characterising private and shared signatures of positive selection in 37 Asian populations

Yazar: Liu, Xuanyao, Lu, Dongsheng, Saw, Woei-Yuh, Shaw, Philip J, Wangkumhang, Pongsakorn, Ngamphiw, Chumpol, Fucharoen, Suthat, Lert-itthiporn, Worachart, Chin-inmanu, Kwanrutai, Chau, Tran Nguyen Bich, Anders, Katie, Kasturiratne, Anuradhani, de Silva, H Janaka, Katsuya, Tomohiro, Kimura, Ryosuke, Nabika, Toru, Ohkubo, Takayoshi, Tabara, Yasuharu, Takeuchi, Fumihiko, Yamamoto, Ken, Yokota, Mitsuhiro, Mamatyusupu, Dolikun, Yang, Wenjun, Chung, Yeun-Jun, Jin, Li, Hoh, Boon-Peng, Wickremasinghe, Ananda R, Ong, RickTwee-Hee, Khor, Chiea-Chuen, Dunstan, Sarah J, Simmons, Cameron, Tongsima, Sissades, Suriyaphol, Prapat, Kato, Norihiro, Xu, Shuhua, Teo, Yik-Ying
Yayımlandı Eur J Hum Genet (2017)

Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees

Yazar: Jun, Goo, Manning, Alisa, Almeida, Marcio, Zawistowski, Matthew, Wood, Andrew R., Teslovich, Tanya M., Fuchsberger, Christian, Feng, Shuang, Cingolani, Pablo, Gaulton, Kyle J., Dyer, Thomas, Blackwell, Thomas W., Chen, Han, Chines, Peter S., Choi, Sungkyoung, Churchhouse, Claire, Fontanillas, Pierre, King, Ryan, Lee, SungYoung, Lincoln, Stephen E., Trubetskoy, Vasily, DePristo, Mark, Fingerlin, Tasha, Grossman, Robert, Grundstad, Jason, Heath, Alison, Kim, Jayoun, Kim, Young Jin, Laramie, Jason, Lee, Jaehoon, Li, Heng, Liu, Xuanyao, Livne, Oren, Locke, Adam E., Maller, Julian, Mazur, Alexander, Morris, Andrew P., Pollin, Toni I., Ragona, Derek, Reich, David, Rivas, Manuel A., Scott, Laura J., Sim, Xueling, Tearle, Rick G., Teo, Yik Ying, Williams, Amy L., Zöllner, Sebastian, Curran, Joanne E., Peralta, Juan, Akolkar, Beena, Bell, Graeme I., Burtt, Noël P., Cox, Nancy J., Florez, Jose C., Hanis, Craig L., McKeon, Catherine, Mohlke, Karen L., Seielstad, Mark, Wilson, James G., Atzmon, Gil, Below, Jennifer E., Dupuis, Josée, Nicolae, Dan L., Lehman, Donna, Park, Taesung, Won, Sungho, Sladek, Robert, Altshuler, David, McCarthy, Mark I., Duggirala, Ravindranath, Boehnke, Michael, Frayling, Timothy M., Abecasis, Gonçalo R., Blangero, John
Yayımlandı Proc Natl Acad Sci U S A (2018)