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Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic

BACKGROUND: Uracil DNA glycosylase (UDG) plays a major role in repair of uracil formed due to deamination of cytosine. UDG in human cells is present in both the nucleus and mitochondrial compartments. Although, UDG's role in the nucleus is well established its role in mitochondria is less clear...

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Publicat a:Mol Cancer
Autors principals: Kachhap, Sushant, Singh, Keshav K
Format: Artigo
Idioma:Inglês
Publicat: BMC 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15574194/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1476-4598-3-32
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