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Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic

BACKGROUND: Uracil DNA glycosylase (UDG) plays a major role in repair of uracil formed due to deamination of cytosine. UDG in human cells is present in both the nucleus and mitochondrial compartments. Although, UDG's role in the nucleus is well established its role in mitochondria is less clear. RES...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cancer
Prif Awduron: Kachhap, Sushant, Singh, Keshav K
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15574194/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1476-4598-3-32
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