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Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic

BACKGROUND: Uracil DNA glycosylase (UDG) plays a major role in repair of uracil formed due to deamination of cytosine. UDG in human cells is present in both the nucleus and mitochondrial compartments. Although, UDG's role in the nucleus is well established its role in mitochondria is less clear...

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Détails bibliographiques
Auteurs principaux: Kachhap, Sushant, Singh, Keshav K
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC538255/
https://ncbi.nlm.nih.gov/pubmed/15574194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-3-32
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