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Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic

BACKGROUND: Uracil DNA glycosylase (UDG) plays a major role in repair of uracil formed due to deamination of cytosine. UDG in human cells is present in both the nucleus and mitochondrial compartments. Although, UDG's role in the nucleus is well established its role in mitochondria is less clear...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cancer
Main Authors: Kachhap, Sushant, Singh, Keshav K
Format: Artigo
Jezik:Inglês
Izdano: BMC 2004
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15574194/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1476-4598-3-32
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