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Silencing Uracil-DNA glycosylase inhibits colorectal cancer progression

Abstract Dysregulation of repair pathways, specifically the base excision repair (BER) axis, is frequently observed in cancer. This dysfunction is associated with accelerated tumor growth and reduced patient survival, suggesting that BER components may serve as potential targets for cancer therapy....

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Autori principali: Jing-jing Yang, Li-zhou Shi, Yong-wei Hu, Hua Chen, Qing-hua Wang, Wei Han
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2026-01-01
Serie:Cancer Cell International
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Accesso online:https://doi.org/10.1186/s12935-025-04089-y
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