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Mitochondrial inhibition of uracil-DNA glycosylase is not mutagenic
BACKGROUND: Uracil DNA glycosylase (UDG) plays a major role in repair of uracil formed due to deamination of cytosine. UDG in human cells is present in both the nucleus and mitochondrial compartments. Although, UDG's role in the nucleus is well established its role in mitochondria is less clear...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC538255/ https://ncbi.nlm.nih.gov/pubmed/15574194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-3-32 |
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