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Myelin-specific multiple sclerosis antibodies cause complement-dependent oligodendrocyte loss and demyelination
Intrathecal immunoglobulin G (IgG) synthesis, cerebrospinal fluid (CSF) oligoclonal IgG bands and lesional IgG deposition are seminal features of multiple sclerosis (MS) disease pathology. Both the specific targets and pathogenic effects of MS antibodies remain poorly characterized. We produced IgG1...
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| 出版年: | Acta Neuropathol Commun |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5366134/ https://ncbi.nlm.nih.gov/pubmed/28340598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0428-6 |
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