The demyelinating potential of antibodies to myelin oligodendrocyte glycoprotein is related to their ability to fix complement.

A panel of 13 monoclonal antibodies (mAbs) has been raised to the central nervous system-specific glycoprotein, myelin oligodendrocyte glycoprotein; five of these mAbs recognize a carbohydrate epitope on the molecule. Although all of the mAbs recognized surface epitopes on cultured oligodendrocytes...

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Main Authors: Piddlesden, S. J., Lassmann, H., Zimprich, F., Morgan, B. P., Linington, C.
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887024/
https://ncbi.nlm.nih.gov/pubmed/7688186
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