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In silico study of amyloid β-protein folding and oligomerization

Experimental findings suggest that oligomeric forms of the amyloid β protein (Aβ) play a critical role in Alzheimer's disease. Thus, elucidating their structure and the mechanisms of their formation is critical for developing therapeutic agents. We use discrete molecular dynamics simulations an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Urbanc, B., Cruz, L., Yun, S., Buldyrev, S. V., Bitan, G., Teplow, D. B., Stanley, H. E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC536046/
https://ncbi.nlm.nih.gov/pubmed/15583128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408153101
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