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In silico study of amyloid β-protein folding and oligomerization
Experimental findings suggest that oligomeric forms of the amyloid β protein (Aβ) play a critical role in Alzheimer's disease. Thus, elucidating their structure and the mechanisms of their formation is critical for developing therapeutic agents. We use discrete molecular dynamics simulations an...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC536046/ https://ncbi.nlm.nih.gov/pubmed/15583128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408153101 |
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