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Dynamics of Metastable β-hairpin Structures in the Folding Nucleus of Amyloid β-Protein

The amyloid β-protein (Aβ), which is present predominately as a 40- or 42-residue peptide, is postulated to play a seminal role in the pathogenesis of Alzheimer's disease (AD). Folding of the Aβ(21–30) decapeptide region is a critical step in the aggregation of Aβ. We report results of constant...

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Detaylı Bibliyografya
Asıl Yazarlar: Cruz, L, Srinivasa Rao, J, Teplow, D. B., Urbanc, B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394227/
https://ncbi.nlm.nih.gov/pubmed/22587454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp301619v
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