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Role of Electrostatic Interactions in Amyloid β-Protein (Aβ) Oligomer Formation: A Discrete Molecular Dynamics Study

Pathological folding and oligomer formation of the amyloid β-protein (Aβ) are widely perceived as central to Alzheimer's disease. Experimental approaches to study Aβ self-assembly provide limited information because most relevant aggregates are quasi-stable and inhomogeneous. We apply a discret...

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Detalhes bibliográficos
Main Authors: Yun, Sijung, Urbanc, B., Cruz, L., Bitan, G., Teplow, D. B., Stanley, H. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868995/
https://ncbi.nlm.nih.gov/pubmed/17307823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.097766
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