Molecular Dynamics Simulation of Amyloid β Dimer Formation

Recent experiments with amyloid β (Aβ) peptide indicate that formation of toxic oligomers may be an important contribution to the onset of Alzheimer's disease. The toxicity of Aβ oligomers depends on their structure, which is governed by assembly dynamics. Due to limitations of current experime...

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Detalhes bibliográficos
Main Authors: Urbanc, B., Cruz, L., Ding, F., Sammond, D., Khare, S., Buldyrev, S. V., Stanley, H. E., Dokholyan, N. V.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Biophysical Theory and Modeling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304655/
https://ncbi.nlm.nih.gov/pubmed/15454432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.040980
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