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Molecular Dynamics Simulation of Amyloid β Dimer Formation

Recent experiments with amyloid β (Aβ) peptide indicate that formation of toxic oligomers may be an important contribution to the onset of Alzheimer's disease. The toxicity of Aβ oligomers depends on their structure, which is governed by assembly dynamics. Due to limitations of current experime...

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Autors principals: Urbanc, B., Cruz, L., Ding, F., Sammond, D., Khare, S., Buldyrev, S. V., Stanley, H. E., Dokholyan, N. V.
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304655/
https://ncbi.nlm.nih.gov/pubmed/15454432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.040980
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