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Noncanonical NF-κB mediates the Suppressive Effect of Neutrophil Elastase on IL-8/CXCL8 by Inducing NKRF in Human Airway Smooth Muscle

Neutrophil elastase (NE) suppresses IL-8/CXCL8 in human airway smooth muscle cells (hASM) while stimulating its production in respiratory epithelial cells. This differential effect is mediated by the selective induction of NKRF and dysregulation in chronic inflammatory diseases. We hypothesized that...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Ho, Shu-Chuan, Wu, Sheng-Ming, Feng, Po-Hao, Liu, Wen-Te, Chen, Kuan-Yuan, Chuang, Hsiao-Chi, Chan, Yao-Fei, Kuo, Lu-Wei, Lee, Kang-Yun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359717/
https://ncbi.nlm.nih.gov/pubmed/28322300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44930
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