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PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema

BACKGROUND: Chronic pulmonary obstructive disease (COPD) has become the fourth leading cause of death worldwide. Cigarette smoking induces neutrophil elastase (NE) and contributes to COPD, but the detailed mechanisms involved are not fully established. In an animal model of pulmonary emphysema, ther...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Hou, Hsin-Han, Cheng, Shih-Lung, Chung, Kuei-Pin, Wei, Shu-Chen, Tsao, Po-Nien, Lu, Hsuan-Hsuan, Wang, Hao-Chien, Yu, Chong-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267747/
https://ncbi.nlm.nih.gov/pubmed/25186164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0106-1
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