PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema

BACKGROUND: Chronic pulmonary obstructive disease (COPD) has become the fourth leading cause of death worldwide. Cigarette smoking induces neutrophil elastase (NE) and contributes to COPD, but the detailed mechanisms involved are not fully established. In an animal model of pulmonary emphysema, ther...

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Dades bibliogràfiques
Publicat a:Respir Res
Autors principals: Hou, Hsin-Han, Cheng, Shih-Lung, Chung, Kuei-Pin, Wei, Shu-Chen, Tsao, Po-Nien, Lu, Hsuan-Hsuan, Wang, Hao-Chien, Yu, Chong-Jen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267747/
https://ncbi.nlm.nih.gov/pubmed/25186164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0106-1
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