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PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema

BACKGROUND: Chronic pulmonary obstructive disease (COPD) has become the fourth leading cause of death worldwide. Cigarette smoking induces neutrophil elastase (NE) and contributes to COPD, but the detailed mechanisms involved are not fully established. In an animal model of pulmonary emphysema, ther...

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Bibliographische Detailangaben
Veröffentlicht in:Respir Res
Hauptverfasser: Hou, Hsin-Han, Cheng, Shih-Lung, Chung, Kuei-Pin, Wei, Shu-Chen, Tsao, Po-Nien, Lu, Hsuan-Hsuan, Wang, Hao-Chien, Yu, Chong-Jen
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267747/
https://ncbi.nlm.nih.gov/pubmed/25186164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0106-1
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