PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema

BACKGROUND: Chronic pulmonary obstructive disease (COPD) has become the fourth leading cause of death worldwide. Cigarette smoking induces neutrophil elastase (NE) and contributes to COPD, but the detailed mechanisms involved are not fully established. In an animal model of pulmonary emphysema, ther...

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Vydáno v:Respir Res
Hlavní autoři: Hou, Hsin-Han, Cheng, Shih-Lung, Chung, Kuei-Pin, Wei, Shu-Chen, Tsao, Po-Nien, Lu, Hsuan-Hsuan, Wang, Hao-Chien, Yu, Chong-Jen
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267747/
https://ncbi.nlm.nih.gov/pubmed/25186164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0106-1
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