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Mitochondrial Ca(2+) Uniporter is a Mitochondrial Luminal Redox Sensor That Augments MCU Channel Activity

Ca(2+) dynamics and oxidative signaling are fundamental mechanisms for mitochondrial bioenergetics and cell function. The MCU complex is the major pathway by which these signals are integrated in mitochondria. Whether and how these coactive elements interact with MCU has not been established. As an...

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Dong, Zhiwei, Shanmughapriya, Santhanam, Tomar, Dhanendra, Siddiqui, Naveed, Lynch, Solomon, Nemani, Neeharika, Breves, Sarah L., Zhang, Xueqian, Tripathi, Aparna, Palaniappan, Palaniappan, Riitano, Massimo F., Worth, Alison, Seelam, Ajay, Carvalho, Edmund, Subbiah, Ramasamy, Jaña, Fabián, Soboloff, Jonathan, Peng, Yizhi, Cheung, Joseph Y., Joseph, Suresh K., Caplan, Jeffrey, Rajan, Sudarsan, Stathopulos, Peter B., Madesh, Muniswamy
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357178/
https://ncbi.nlm.nih.gov/pubmed/28262504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.01.032
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