Ca(2+) signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca(2+) uniporter gene mcu

Cytosolic Ca(2+) signals, generated through the coordinated translocation of Ca(2+) across the plasma membrane (PM) and endoplasmic reticulum (ER) membrane, mediate diverse cellular responses. Mitochondrial Ca(2+) is important for mitochondrial function and, when cytosolic Ca(2+) concentrations beco...

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Publicado no:Sci Signal
Main Authors: Shanmughapriya, Santhanam, Rajan, Sudarsan, Hoffman, Nicholas E., Zhang, Xueqian, Guo, Shuchi, Kolesar, Jill E., Hines, Kevin J., Ragheb, Jonathan, Jog, Neelakshi R., Caricchio, Roberto, Baba, Yoshihiro, Zhou, Yandong, Kaufman, Brett, Cheung, Joseph Y., Kurosaki, Tomohiro, Gill, Donald L., Madesh, Muniswamy
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722812/
https://ncbi.nlm.nih.gov/pubmed/25737585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005673
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