The development of novel LTA(4)H modulators to selectively target LTB(4) generation

The pro-inflammatory mediator leukotriene B(4) (LTB(4)) is implicated in the pathologies of an array of diseases and thus represents an attractive therapeutic target. The enzyme leukotriene A(4) hydrolase (LTA(4)H) catalyses the distal step in LTB(4) synthesis and hence inhibitors of this enzyme hav...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Low, Caroline M., Akthar, Samia, Patel, Dhiren F., Löser, Stephan, Wong, Chi-Tung, Jackson, Patricia L., Blalock, J. Edwin, Hare, Stephen A., Lloyd, Clare M., Snelgrove, Robert J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355877/
https://ncbi.nlm.nih.gov/pubmed/28303931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44449
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia