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A critical role for LTA(4)H in limiting chronic pulmonary neutrophilic inflammation
Leukotriene A(4) Hydrolase (LTA(4)H) is a pro-inflammatory enzyme which generates the inflammatory mediator leukotriene B(4) (LTB(4)). LTA(4)H also possesses aminopeptidase activity with unknown substrate and physiological significance. We identified the neutrophil chemoattractant, Pro-Gly-Pro (PGP)...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072752/ https://ncbi.nlm.nih.gov/pubmed/20813919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1190594 |
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