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Transactivation of E2F-Regulated Genes by Polyomavirus Large T Antigen: Evidence for a Two-Step Mechanism

Polyomavirus large T antigen transactivates a variety of genes whose products are involved in S phase induction. These genes are regulated by the E2F family of transcription factors, which are under the control of the pocket protein retinoblastoma protein and its relatives p130 and p107. The viral p...

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Autori principali: Nemethova, Maria, Smutny, Michael, Wintersberger, Erhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC533978/
https://ncbi.nlm.nih.gov/pubmed/15572699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10986-10994.2004
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