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Optimal replication of plasmids carrying polyomavirus origin regions requires two high-affinity binding sites for large T antigen.

The efficiency of replication of plasmids containing the control region of polyomavirus DNA including one, two, or all three of the strong binding sites for large T antigen was measured in COP 8 cells which provide polyomavirus T antigen in trans. It was found that plasmids carrying only binding sit...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Weichselbraun, I, Haider, G, Wintersberger, E
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1989
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536118/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.2.961-964.1989
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