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Transactivation of E2F-Regulated Genes by Polyomavirus Large T Antigen: Evidence for a Two-Step Mechanism

Polyomavirus large T antigen transactivates a variety of genes whose products are involved in S phase induction. These genes are regulated by the E2F family of transcription factors, which are under the control of the pocket protein retinoblastoma protein and its relatives p130 and p107. The viral p...

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Bibliographic Details
Main Authors: Nemethova, Maria, Smutny, Michael, Wintersberger, Erhard
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC533978/
https://ncbi.nlm.nih.gov/pubmed/15572699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10986-10994.2004
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