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Transactivation of E2F-Regulated Genes by Polyomavirus Large T Antigen: Evidence for a Two-Step Mechanism

Polyomavirus large T antigen transactivates a variety of genes whose products are involved in S phase induction. These genes are regulated by the E2F family of transcription factors, which are under the control of the pocket protein retinoblastoma protein and its relatives p130 and p107. The viral p...

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Detalhes bibliográficos
Main Authors: Nemethova, Maria, Smutny, Michael, Wintersberger, Erhard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC533978/
https://ncbi.nlm.nih.gov/pubmed/15572699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.24.10986-10994.2004
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