Protein Transduction Domains Fused to Virus Receptors Improve Cellular Virus Uptake and Enhance Oncolysis by Tumor-Specific Replicating Vectors

Expression of cellular receptors determines viral tropism and limits gene delivery by viral vectors. Protein transduction domains (PTDs) have been shown to deliver proteins, antisense oligonucleotides, liposomes, or plasmid DNA into cells. In our study, we investigated the role of several PTD motifs...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Kühnel, Florian, Schulte, Bernd, Wirth, Thomas, Woller, Norman, Schäfers, Sonja, Zender, Lars, Manns, Michael, Kubicka, Stefan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2004
Teme:
Gene Therapy
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC533898/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15564483/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.24.13743-13754.2004
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