Protein Transduction Domains Fused to Virus Receptors Improve Cellular Virus Uptake and Enhance Oncolysis by Tumor-Specific Replicating Vectors

Expression of cellular receptors determines viral tropism and limits gene delivery by viral vectors. Protein transduction domains (PTDs) have been shown to deliver proteins, antisense oligonucleotides, liposomes, or plasmid DNA into cells. In our study, we investigated the role of several PTD motifs...

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Detalhes bibliográficos
Main Authors: Kühnel, Florian, Schulte, Bernd, Wirth, Thomas, Woller, Norman, Schäfers, Sonja, Zender, Lars, Manns, Michael, Kubicka, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Gene Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC533898/
https://ncbi.nlm.nih.gov/pubmed/15564483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13743-13754.2004
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