Protein Transduction Domains Fused to Virus Receptors Improve Cellular Virus Uptake and Enhance Oncolysis by Tumor-Specific Replicating Vectors

Expression of cellular receptors determines viral tropism and limits gene delivery by viral vectors. Protein transduction domains (PTDs) have been shown to deliver proteins, antisense oligonucleotides, liposomes, or plasmid DNA into cells. In our study, we investigated the role of several PTD motifs...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kühnel, Florian, Schulte, Bernd, Wirth, Thomas, Woller, Norman, Schäfers, Sonja, Zender, Lars, Manns, Michael, Kubicka, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Gene Therapy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC533898/
https://ncbi.nlm.nih.gov/pubmed/15564483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13743-13754.2004
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi