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Doxycyline regulation in a single retroviral vector by an autoregulatory loop facilitates controlled gene expression in liver cells

The tetracycline system has limitations in liver cells, such as toxic effects and low controllability. We generated different retroviral vectors for controlled gene expression in liver cells, in which the regulatory elements were arranged in different patterns. Only the organization of the tetracycl...

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Detalhes bibliográficos
Main Authors: Kühnel, Florian, Fritsch, Corinna, Krause, Sabine, Mundt, Bettina, Wirth, Thomas, Paul, Yasmin, Malek, Nisar Peter, Zender, Lars, Manns, Michael Peter, Kubicka, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC373428/
https://ncbi.nlm.nih.gov/pubmed/14966262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh034
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