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Doxycyline regulation in a single retroviral vector by an autoregulatory loop facilitates controlled gene expression in liver cells

The tetracycline system has limitations in liver cells, such as toxic effects and low controllability. We generated different retroviral vectors for controlled gene expression in liver cells, in which the regulatory elements were arranged in different patterns. Only the organization of the tetracycl...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Kühnel, Florian, Fritsch, Corinna, Krause, Sabine, Mundt, Bettina, Wirth, Thomas, Paul, Yasmin, Malek, Nisar Peter, Zender, Lars, Manns, Michael Peter, Kubicka, Stefan
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373428/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14966262/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh034
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