Virus-induced tumor inflammation facilitates effective DC cancer immunotherapy in a Treg-dependent manner in mice

Vaccination using DCs pulsed with tumor lysates or specific tumor-associated peptides has so far yielded limited clinical success for cancer treatment, due mainly to the low immunogenicity of tumor-associated antigens. In this study, we have identified intratumoral virus-induced inflammation as a pr...

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Detalhes bibliográficos
Main Authors: Woller, Norman, Knocke, Sarah, Mundt, Bettina, Gürlevik, Engin, Strüver, Nina, Kloos, Arnold, Boozari, Bita, Schache, Peter, Manns, Michael P., Malek, Nisar P., Sparwasser, Tim, Zender, Lars, Wirth, Thomas C., Kubicka, Stefan, Kühnel, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223834/
https://ncbi.nlm.nih.gov/pubmed/21646722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45585
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