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Doxycyline regulation in a single retroviral vector by an autoregulatory loop facilitates controlled gene expression in liver cells

The tetracycline system has limitations in liver cells, such as toxic effects and low controllability. We generated different retroviral vectors for controlled gene expression in liver cells, in which the regulatory elements were arranged in different patterns. Only the organization of the tetracycl...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kühnel, Florian, Fritsch, Corinna, Krause, Sabine, Mundt, Bettina, Wirth, Thomas, Paul, Yasmin, Malek, Nisar Peter, Zender, Lars, Manns, Michael Peter, Kubicka, Stefan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC373428/
https://ncbi.nlm.nih.gov/pubmed/14966262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh034
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